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Role of copeptin in pediatric health and diseases

Volume No : (2016) Volume: 04 Issue : 21 Year : 2016 Page No: 150-154

Authors : Bandya Sahoo

Abstract :

Copeptin, a precursor of vasopressin is released when the hypothalamic-pituitary-adrenal axis (HPA) is activated in response to stress. Copeptin secretion from the posterior pituitary gland is in equimolar amounts with arginine vasopressin, hence it reflects arginine vasopressin concentration and can be used as surrogate biomarker of arginine vasopressin secretion. Measurement of copeptin levels has been shown to be useful in a variety of clinical scenarios. Therefore it can be used as a novel diagnostic and prognostic biomarker in pediatric diseases. The purpose of the present article is to highlight the role of copeptin as a prognostic marker in different pediatric illnesses where it may help in early detection and diagnostic accuracy.

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